The proportionate weight of progesterone in an grownup human could be a number of grams per day. On a weight and quantity basis, this can be like injecting an grownup human with greater than a quart of sesame oil daily for five days. In one other examine printed in 1977 (Iguchi and Takasugi) neonatal mice had been given the same day by day amount of progesterone, however for ten days somewhat than five, giving them twice the dose. That amount of progesterone (3% weight/quantity) will dissolve in sizzling corn oil, however because the oil cools, the progesterone crystallizes and precipitates. This amount of progesterone is excess of the anesthetic dose. Excess estrogen causes the virus to be expressed, progesterone opposes its expression. Jones and Bern injected the newborn mice with 0.02 ml of sesame oil daily for five days, with or without estrogen and progesterone. Estrogen increases the manufacturing of mucus in the cervix and vagina, and will increase its water content material and mobility. Progesterone makes the mucus more viscous and fewer hydrophilic, and when it dominates the reproductive physiology, it effectively creates a plug in the cervix that prevents the entry of sperms. That creates doubt relating to what the animals have been actually receiving. The animals obtained 2 ml of corn oil in the stomach feeding with the carcinogen.
Unfortunately, there was no management group during which the corn oil was injected alone. This research might need had the formal appearance of a scientific experiment, but the unfamiliarity of the males with the fabric they were using, their use of mice carrying the mammary tumor virus, and, extra importantly, the extraordinarily advanced reactions produced when extraneous supplies are injected into the tissues, make this a ineffective experiment. The progesterone was injected subcutaneously in three mg doses in corn oil thrice per week. Instead, you must put together your meals and embrace healthy fats like fatty beef cuts, cheese and alternative farm product, egg yolks, oil and bittersweet chocolate all which include saturated fats. One of the groups (group 5) obtained, in addition, more than 6 ml of corn oil in the injections. Corn oil is one in all the most effective vegetable oil tumor promoters/carcinogens, and it is now thought of improper to use it as a solvent for testing even oral carcinogens, since some chemicals that are carcinogenic in the oil are comparatively harmless when administered without the corn oil. Since the usage of purple umbrellas by intercourse employees in Venice, Italy, in 2001-as part of the 49th Venice Biennale of Art-a purple umbrella has develop into the foremost internationally acknowledged symbol for intercourse worker rights.
Within the horror genre, and particularly the slasher subgenre, there is heavy use of a character labeled “The Final Girl.” This is the female protagonist of the movie that’s the last character left alive, and the one that stops, or evades, the antagonist. The progesterone was supposedly dissolved within the corn oil, one tenth ml per dose. This later publication appears to clarify the which means of nodules or tumors in the youthful animals: “Although mammary tumors have been observed neither in management nor in progesterone-handled intact mice, most of the latter group possessed hyperplastic alveolar-like mammary nodules and other dysplasias.” Neither of those studies refers back to the carcinogenicity of progesterone. Anyone working with mammary tumor virus-bearing mice in the 1970s should have been aware of the results of intercourse hormones on the expression of virus and development of most cancers within the infected mice, as studied by Strong, Figge, and others for about 40 years. The 1977 study (at the University of California, Berkeley) was explicitly motivated by Jones’ and Bern’s concern with the dangers of the medical follow of treating pregnant ladies with DES and a artificial progestin, and so they used mammary tumor virus-bearing mice, and they did not continue the research to observe the incidence of precise cancers.
Jones’ and Bern’s paper described the production, 12 months after neonatal remedy with progesterone, of vaginal and cervical lesions, and mammary nodules, that are additionally known as tumors. Two different studies cited by the IARC and different agencies, by Jones and Bern, 1977, and Rebout and Pageaut, hardly appear applicable research to help the idea that progesterone is carcinogenic. Fans crawled out of the woodwork to assist the kooky, redheaded comedian. He couldn’t be so silly that I needed to spell out the remainder for him, might he? Liebenthal mentioned he killed him, but I just checked with Agape. In one other 1977 publication, Jones, Bern, and Wong described modifications seen when the mice had been 1.5 to 2 years outdated. In their second 1977 examine, Jones, Bern and Wong reported that at the age of 1.5 to 2 years, almost two thirds of the progesterone treated mice had genital tract lesions.